منابع مشابه
Action of vitamin K on bone health
Objetives: Nowadays it is recognised that vitamin K plays an important role in bone health. It is necessary for the gamma-carboxylation of osteocalcin (the most important non-collagen protein in the bone), making the osteocalcin function. There are two important forms of vitamin K (vitamin K1 and vitamin K2), which come from different sources and have different biological activity. Epidemiologi...
متن کاملVitamin K and metabolic bone disease.
Originally, vitamin K was defined as a factor concerned with haemostasis, deficiency resulting in a haemorrhagic disease. After the initial discovery of phylloquinone in 1929, various compounds were described which all had “vitamin K activity,” that is, the ability to restore normal haemostasis in vitamin K deficient animals. It turned out that “vitamin K” is a group name for several related co...
متن کاملVitamin K2 and Bone Health
During the last 20 years, the main clinical effects of vitamin K2 on bone homeostasis have been investigated in both indirect and direct vitamin K treatment regimens. This chapter is mainly based on randomized clinical trials (RCT) lasting for more than 1 year. As for vitamin K1 (phylloquinone, indirect treatment) and vitamin K2 (menaquinone MK‐4 and MK‐7 direct treatment), respectively, the cl...
متن کاملVitamin D and bone health
Throughout the life-cycle, the skeleton requires optimum development and maintenance of its integrity to prevent fracture. Bones break because the loads placed upon them exceed the ability of the bone to absorb the energy involved. It is now estimated that 1:3 women and 1:12 men over the age of 55 years will suffer from osteoporosis in their lifetime and in the UK, at a cost in excess of £1.7 b...
متن کاملVitamin D and Bone Health
The vitamin D3 molecule, or cholecalciferol, is now considered a hormone that acts on multiple homeostatic fronts, either skeletal or extra-skeletal. After 100 years since from its identification as a protective and curative factor of rickets, during the last decade the interest in vitamin D among scientists and general public increased substantially and the use of vitamin D supplements has inc...
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ژورنال
عنوان ژورنال: Proceedings of the Nutrition Society
سال: 2003
ISSN: 0029-6651,1475-2719
DOI: 10.1079/pns2003305